Part:BBa_K3956006:Design

Since the original Scl2 does not have a cleaving domain that is recognizable by MMP collagenase or other enzyme proteins, it was important to introduce an enzyme cleaning domain that allows for it to be recognized and cleaved by human MMP collagenase.

Yu, Zhuoxin, et al. “Defining Requirements For Collagenase Cleavage in Collagen Type III Using a Bacterial Collagen System.” The Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 29 June 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3391134/.